PLoS: Building Clinical Trials Capacity For Tuberculosis Drugs in High-Burden Countries

Authors: Neil Schluger, Unni Karunakara, Christian Lienhardt, Thomas Nyirenda and Richard Chaisson

To improve TB treatment in the near future, a large number of clinical trials should be carried out to examine alternative regimens using existing drugs and the modest but growing pipeline of new compounds. The capacity to conduct a serious clinical trials agenda in high-burden countries needs to be built up as soon as possible.