The COVID-19 pandemic has already spread to more than 100 countries around the world. These include countries whose health systems are fragile and where MSF teams have a long-standing presence, as well as regions such as Europe, where the capacities are more robust but where the epidemic is particularly virulent. Travel restrictions generated by the outbreak also directly affect MSF's work around the world. What questions does MSF face in this context? Dr Clair Mills, MSF’s medical director, explains the challenges.