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In medical journals/research articles
Introduction Of the 24 neglected tropical diseases (NTDs) and conditions listed by WHO, snakebite is among the top killers . Tens of thousands die each year as a result of snakebite envenoming, with close to 50,000 deaths in India alone  and up to 32,000 in sub-Saharan Africa . Yet there are few sources of effective, safe and affordable antivenoms. The regions that bear the highest snakebite burden are especially underserved .
Last updated 10 September 2015
Impact of Pneumococcal Conjugate Vaccine Administration in Pediatric Older Age Groups in Low and Middle Income Countries: A Systematic Review.
Last updated 2 September 2015
Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds
HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for whole blood and plasma. Data from various studies indicate that HIV RNA is stable beyond current recommendations. We conducted a systematic review to assess stability data of HIV RNA in whole blood and plasma across times and temperatures.
Last updated 2 December 2014
Dried blood spot in the genotyping, quantification and storage of HCV RNA: a systematic literature review
SUMMARY. The entry of new all-oral direct acting antiviral therapy for hepatitis C provides an opportunity to scale up HCV care in low- and middle-income countries. In HIV, use of dried blood spots (DBS) has facilitated the diagnosis and management of HIV in resource-poor settings. DBS may be used in a similar way to facilitate diagnosis and management of HCV.
Objectives Further scale-up of antiretroviral therapy (ART) to those in need while supporting the growing patient cohort on ART requires continuous adaptation of healthcare delivery models. We describe several approaches to manage stable patients on ART developed by Médecins Sans Frontières together with Ministries of Health in four countries in sub-Saharan Africa. Methods
Last updated 19 June 2014
Pathway to affordable, quality-assured sources of pegylated interferon alpha for treating hepatitis C
Introduction: The current pipeline of promising oral hepatitis C drugs could lead to a revolution in treatment for this disease in both developed and developing countries. At present, the recommended treatment is pegylated interferon alpha (in combination with ribavirin). However, the limited availability and high cost of this medicine is a major barrier to expanding access to treatment in developing countries.
Last updated 7 February 2014
Access to liposomal generic formulations: beyond AmBisome and Doxil/Caelyx Abstract:
Last updated 14 June 2013
Adverse events associated with nevirapine and efavirenz-based first-line antiretroviral therapy: a systematic review and meta-analysis
Introduction: Since 2002, the WHO has recommended either nevirapine (NVP) or efavirenz (EFV) as part of first-line antiretroviral therapy. These two drugs are known to have differing toxicity profiles, but the risk of these toxicities overall is not well established.
Strategies for reducing treatment default in drug-resistant tuberculosis: systematic review and meta-analysis
BACKGROUND: Scaling up treatment for multi-drug-resistant tuberculosis is a global health priority. However, current treatment regimens are long and associated with side effects, and default rates are consequently high. This systematic review aimed to identify strategies for reducing treatment default.
Last updated 23 February 2013